High Quality Bodybuilding Supplements Sarms Raw Powder Gw-501516 Cardarine GSK-516
  • Vote Up0Vote Down venynxvenynx
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    GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist
    that has been demonstrated to be 1,000-fold more selective in comparison
    to existing subtypes.

    Studies demonstrate that GW501516 can regulate expression of genes
    involved in lipid catabolism and energy uncoupling in skeletal muscle
    cells. Additionally, GW501516 has been shown to block insulin resistance
    and fatty acid-induced nuclear factor-κB (NF-κB) activation.Raw Cardarine powder


    Cardarine (GW-501516) binds to the PPAR receptor, specifically a
    group of nuclear receptors (sensors that detect thyroid and steroidal
    hormones in the body) that initiates the PGC-1a enzyme. This action
    leads to gene expression, specifically genes that revolve around energy

    Studies involving GW-501516 have shown to increase the metabolism of
    fatty acids in rats. It was also shown in the same studies to reduce the
    odds of obesity despite poor eating habits as well as prevent Type-2
    diabetes. Cardarine was also shown to increase HDL (good cholesterol)
    and decrease LDL (bad cholesterol) in a study using monkeys. The effects
    seemed to hold true with or without exercise.

    Usage and Dosage :

    There are two main uses with GW-501516. The first and most common use
    is that of increased endurance. GW has been banned for professional
    athletes due to the unfair advantage it provides to endurance athletes.
    Anyone want a drastic increase in endurance will find that GW truly
    shines in this aspect. It takes effect very quickly and the results can
    be staggering. A common dose of 10 mg day will provide a significant
    increase in endurance.

    The second common usage with GW is that of fat loss. Many users turn
    to GW as it has shown to melt off fat while still being non-catabolic.
    You will find that you can still hold on to some muscle as you are
    losing fat. It helps when you are running it in conjunction with SARMS
    Ostarine and S4, to hold on to as much muscle as possible. A dosage of
    10 mg a day will provide good amounts of fat loss, but an increase to 20
    mg a day will provide much more in this area.

    GW 501516 can be ran in 8 week cycles, but as with any other steroid
    or supplement, it should be cycled properly to avoid any possible side
    effects and the keep it as effective as possible.

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